Theravac Biologics

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TheraVac Biologics

Active Immunotherapies for Chronic and
Neurodegenerative Diseases

TheraVac Biologics is developing novel immunotherapies for diseases caused by misfolded protein aggregates and/or chronic inflammation.
ABOUT THERAVAC

Our Vision

The current therapeutic approaches have limited efficacy and will not be able to satisfy the increasing demand for treatment of chronic aging-related diseases including Alzheimer’s.

Our Mission

At TheraVac Biologics, we are aiming to develop safe and effective immunotherapies for treatment of chronic and neurodegenerative conditions including Alzheimer’s disease.

TheraVac’s Platform Technology

Offering safe, inexpensive, and effective immunotherapies

Platform

Multivalent display of immunogenic peptides on the surface of virus-like particles (VLPs)

Advantage

Elicits strong immune response with no requirements for using pro-inflammatory adjuvants

Regulatory Approval

VLP-based vaccines have been approved by FDA: Gardasil® and Recombivax HB®

Partners and Collaborators

Our lead biologics, TV-301 and TV-202 target key pathways in Alzheimer’s pathology

Offering safe, inexpensive, and effective immunotherapies

NLRP3: nucleotide-binding domain, leucine-rich–containing family, pyrin domain–containing-3
ASC: apoptosis-associated speck-like protein containing a caspase-recruitment domain

Our biologics development pipeline

offering safe, inexpensive, and effective immunotherapies
Biologics / Indication
Development
Preclinical
IND-enabling
Clinical
TV-301 / Alzheimer’s Disease
(prodromal to mild) 73%
TV-202 / Frontotemporal Dementia*
66%
TV-400 / Spinal Muscular Atrophy*
50%
TV-100 / TBD
40%

*Orphan disease
TV-100: inflammasome blocking antibody
TBD: to be disclosed

Our Team
At TheraVac Biologics, our leadership and advisory board brings deep expertise across the full spectrum of biologics research, preclinical and clinical development, and strategic business growth. By combining scientific excellence with operational execution and business development expertise, we are uniquely positioned to efficiently advance innovative therapies from discovery through clinical development and toward commercialization.
Ali Riazi

Ali Riazi, PhD

Co-founder & CEO
Kiran Bhaskar

Kiran Bhaskar, PhD

Scientific Co-founder & Advisor
Bryce Chackerian

Bryce Chackerian, PhD

Scientific Co-founder & Advisor
Joseph Endicott

Joseph Endicott, PhD

Scientific co-founder & Advisor
Nikki Maphis

Nicole Maphis, PhD

Senior scientist
paul schulz

Paul Schulz, MD

Clinical Advisor
David Carlson

David Carlson, MSc

Director of Business Development
Laurent Balenci

Laurent Balenci, PhD

Co-founder & Advisor
Bruce Taillon

Bruce Taillon, PhD

Business Advisor - Animal Health
Doris Snow

Doris Snow

Director & Regulatory Affairs

Mark Leivonen

Business Advisor
Aleksei Evteshin

Aleksei Evteshin

Co-founder & Director of Finance
Our Team
At TheraVac Biologics, our leadership and advisory board brings deep expertise across the full spectrum of biologics research, preclinical and clinical development, and strategic business growth. By combining scientific excellence with operational execution and business development expertise, we are uniquely positioned to efficiently advance innovative therapies from discovery through clinical development and toward commercialization.
Ali Riazi

Ali Riazi, PhD

Co-founder & CEO

Kiran Bhaskar

Kiran Bhaskar, PhD

Scientific co-founder & Advisor

Bryce Chackerian

Bryce Chackerian, PhD

Scientific Co-founder & Advisor

Joseph Endicott

Joseph Endicott, PhD

Scientific co-founder & Advisor

Nikki Maphis

Nicole Maphis, PhD

Senior scientist

paul schulz

Paul Schulz, MD

Clinical Advisor

David Carlson

David Carlson, MSc

Director of Business Development

Laurent Balenci

Laurent Balenci, PhD

Co-founder & Advisor

Bruce Taillon

Bruce Taillon, PhD

Business Advisor - Animal Health

Doris Snow

Doris Snow

Director & Regulatory Affairs

Mark Leivonen

Business Advisor

Aleksei Evteshin

Aleksei Evteshin

Co-founder & Director of Finance

Our Team
At TheraVac Biologics, our leadership and advisory board brings deep expertise across the full spectrum of biologics research, preclinical and clinical development, and strategic business growth. By combining scientific excellence with operational execution and business development expertise, we are uniquely positioned to efficiently advance innovative therapies from discovery through clinical development and toward commercialization.